Considering that, it could be argued that she was just speaking out against the simplistic manner women are sometimes portrayed in movies and on television.
First coming to prominence for her work on the show My So-Called Life, after that series ended, it took years for her to return to the medium again until Homeland, which was a massive hit for her.
Introduced to many by her work on Ally McBeal, her most notable role was as Jenna Maroney on 30 Rock, which she played for seven seasons.
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Still, she spent years in the film world with roles in projects like Brokedown Palace, The Hours, Terminator 3: Rise of the Machines, and Shopgirl, to name a few.